A couch-potato mouse? Sanford-Burnham researchers say it holds key to obesity

Posted by on Dec 2nd, 2010 and filed under Lake Nona Med Center. You can follow any responses to this entry through the RSS 2.0. You can leave a response or trackback to this entry

burnham couch potato

Scientists at Orlando’s Sanford-Burnham Medical Research Institute have come up with an unusual new model for studying the way muscles work and how that relates to obesity: a couch-potato mouse.

In a new study being released today in the journal Cell Metabolism, Dr. Daniel Kelly and a team of colleagues at Sanford-Burnham’s Lake Nona campus created laboratory mice with very low levels of a protein called PGC-1 in their muscles.

Kelly and his team were surprised to find that the mice they engineered with the low protein levels were not obese or overweight. Instead, they looked normal and walked around without problems.

Continue Reading